groups may experience no change, or in some cases,
even weight gain. The weight increase may be related
to increased consumption of foods high in sugars and
protein which is common during Ramadan. It is also
customary to eat meals with friends and relatives,
which is conducive to higher food intake. Further, a
decline in respiratory exchange ratio reflecting in-
creased mobilization of body fat is suggestive of a
metabolic adaptation to fasting.
0011 Dehydration due to abstinence from drinking fluids
over long periods of time during Ramadan has been a
cause for some concern, especially in hot tropical
climates. Negative fluid balance among fasting indi-
viduals is evident by increased hematocrit, serum
sodium, calcium, protein, creatinine, urea, and modi-
fied electrolyte balance. Increased concentration of
urine and decreased urine volume and salt retention
are some of the compensatory mechanisms to achieve
fluid balance. The season in which the month of
Ramadan falls may have a big effect on the evapora-
tive water loss that can occur. Studies have shown
conflicting results: some suggest no negative fluid
balance while others show this may be due to envir-
onmental factors such as temperature and humidity
of the place and season in which the studies were
carried out.
0012 The effects of Ramadan fasting on changes in
carbohydrate metabolism are not well-known. Al-
though fasting levels of glucose and insulin tend to
remain unchanged, or decline initially but then return
to normal later, circadian profiles of gastric pH,
plasma gastrin, insulin, glucose, and calcium are
modified during Ramadan. Increased concentrations
of urea and uric acid suggesting increased catabolism
have not always been confirmed.
0013 The effect of Ramadan fasting on plasma lipids
and lipoproteins has received some interest. Almost
consistent reports of no change in total cholesterol
and low-density lipoprotein-cholesterol (LDL-C) and
beneficial increases in high-density lipoprotein chol-
esterol (HDL-C), apo A-1, and apo A-1 to apo B ratio
are found. While these effects may be sustained for
about a month after Ramadan ends, the impact of
such transient annual changes on cardiovascular dis-
ease remains unknown and open for research.
Pregnancy and Lactation and Ramadan Fasting
0014 The rules of exemption from fasting in certain con-
ditions such as during pregnancy or while breast-
feeding an infant appear to have varying degrees of
acceptance and interpretation. In some cultures, preg-
nant women may either be unaware of this exemption
or may choose to fast with the rest of the family rather
than alone, at a later time, due to the inconveniences
of a different meal pattern and cooking. Cases of
unsuccessful lactation due to fasting have led to un-
hygienic alternatives being offered to the young infant
in lieu of breast milk, resulting in adverse health
effects. The effects of dehydration due to abstention
from drinking water during Ramadan on lactational
performance suggest that, although lactating women
may lose some of their total body water during
the daylight hours, plasma indices of dehydration
over a 24-h period remain in a normal range. This
may occur because women adapt by superhydrating
themselves overnight and by restricting urinary
output. Despite these mild changes in their state of
hydration, there may be marked changes in breast
milk osmolality, lactose, sodium, and potassium
concentrations, reflecting disturbed milk synthesis.
Accounts of drastic effects of fasting on young
breast-feeding infants is found in the 1930s when
severe forms of xerophthalmia (clinical signs of vita-
min A deficiency) occurred in infants whose mothers
participated in long-term religious fasts.
0015Scientific knowledge on the health and other
impacts of fasting during pregnancy is scant, although
metabolic consequences of fasting during pregnancy,
such as declines in concentration of serum glucose,
insulin, lactate, creatinine, and a rise in triglycerides
and hydroxybutyrate suggests a state of a phenom-
enon termed as ‘accelerated starvation.’ Although
pregnancy outcome, including birth weight of infants
whose mothers observed Ramadan fast during preg-
nancy, does not appear to be affected in affluent
settings, increased rates of low birth weight, still-
births, and perinatal mortality are observed among
populations living in poor, more stressful environ-
ments. It is hard to determine, however, whether the
adverse outcomes are a direct result of the fasting.
Interestingly, increased full-term births have been
recorded during the 25-h-long fast of Yom Kippur.
The Hindu Conception of Vegetarianism:
The Sacred Cow
0016In the pre-Aryan Indus valley civilization, it was the
bull, not the cow, that was venerated. Cattle were
prized assets and considered objects of worship, as
recounted in the hymns of Rig-Veda, the holy Hindu
scriptures written in 1500–100 bce. The Atharva-
Veda, which came later, is where the first accounts
of the prohibition of the slaughter of cows are found.
While meat eating was practiced, and cows were
occasionally slaughtered for guests and at times of
festivity, the sacredness of the cow, manifest as the
Vahan (carrier) of god Shiva became complete in the
great epic Mahabharata. Here the sanctity of a cow is
recognized and attributed to being a source of food
(milk), promoting fertility, removing evil influences,
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