4th ed. - Wiley. 2008. 949 p.
Molecular and Biochemical Toxicology: Definition and Scope
Overview of Molecular Techniques in Toxicology: Genes and Transgens
Toxicogenomics
Proteomics
Metabolomics
Bioinformatics
Immunochemical Techniques in Toxicology
Celllular Techniques
Structure, Mechanism, and Regulation of Cytochromes P450
Phase I Metabolism of Toxicants and Metabolic Interactions
Phase I - Toxicogenetics
Phase II - Conjugation of Toxicants
Regulation and Polimorphisms in Phase II Genes
Developmental Effects on Xenobiotic Metabolism
Cellular Transport and Elimination
Mechanisms of cell Death
Glutathione-Deoendent Mechanisms in Chemically Induced cell Injury and Cellular Protection Mechanisms
Toxicant-Receptor Interactions: Fundamental Principles
Reactive Oxygen/Reactive Metabolites and Toxicity
Metals
DNA Damage and Mutagenesis
DNA Repair
Carcinogenesis
Genetic Toxicology
Molecular Epidemiology and Genetic Susceptibility
Respiratory Toxicology
Hepatotoxicology
Biochemical Mechanisms of Renal Toxicity
Biochemical Toxicology of the Peripheral Nevous System
Biochemical Toxicology of the Central Nervous System
Immunotoxicology
Reproductive Toxicology
Developmental Toxicology
Dermatotoxicology
Molecular and Biochemical Toxicology: Definition and Scope
Overview of Molecular Techniques in Toxicology: Genes and Transgens
Toxicogenomics
Proteomics
Metabolomics
Bioinformatics
Immunochemical Techniques in Toxicology
Celllular Techniques
Structure, Mechanism, and Regulation of Cytochromes P450
Phase I Metabolism of Toxicants and Metabolic Interactions
Phase I - Toxicogenetics
Phase II - Conjugation of Toxicants
Regulation and Polimorphisms in Phase II Genes
Developmental Effects on Xenobiotic Metabolism
Cellular Transport and Elimination
Mechanisms of cell Death
Glutathione-Deoendent Mechanisms in Chemically Induced cell Injury and Cellular Protection Mechanisms
Toxicant-Receptor Interactions: Fundamental Principles
Reactive Oxygen/Reactive Metabolites and Toxicity
Metals
DNA Damage and Mutagenesis
DNA Repair
Carcinogenesis
Genetic Toxicology
Molecular Epidemiology and Genetic Susceptibility
Respiratory Toxicology
Hepatotoxicology
Biochemical Mechanisms of Renal Toxicity
Biochemical Toxicology of the Peripheral Nevous System
Biochemical Toxicology of the Central Nervous System
Immunotoxicology
Reproductive Toxicology
Developmental Toxicology
Dermatotoxicology