Hermanson G. Bioconjugate Techniques, Second Edition

1110 References

Salmain , M. , Fischer-Durand , N., Cavalier , L. , Rudolf , B., Zakrzewski , J. , and Jaouen , G. ( 2002)

Transition metal-carbonyl labeling of biotin and avidin for use in solid-phase carbonyl metallo immu-

noassay (CMIA) . Bioconjugate Chem. 13 , 693 – 698 .

Salmon , S.E. ( 1989) Monoclonal antibody immunoconjugates for cancer . Antibody, Immunoconjugates,

Radiopharm. 2 , 63 – 70 .

Samaha , R.R. , Joseph , S., O ’Brien, B., O ’Brien, T.W. , and Noller , H.F. ( 1999) Site-directed hydroxyl radi-

cal probing of 30S ribosomal subunits by using Fe(II) tethered to an interruption in the 16S rRNA

chain . PNAS 96 , 366 .

Samal , S., and Geckeler , K.E. ( 2000) Cyclodextrin–fullerenes: a new class of water-soluble fullerenes . J.

Chem. Soc. Chem. Comm. , 1101 – 1102

.

Sammes , P.G. , and Yahioglu , G. ( 1996) Modern bioassays using metal chelates as luminescent probes .

Nat. Prod. Rep. 13 , 1– 28 .

Sanderson , C.J. , and Wilson , D.V. ( 1971) A simple method for coupling proteins to insoluble polysaccha-

rides . Immunology 20 , 1061 – 1065 .

Sandvig , K., and Olsnes , S. ( 1981) Rapid entry of nicked diphtheria toxin into cells at low pH.

Characterization of the entry process and effects of low pH on the toxin molecule . J. Biol. Chem.

256 , 9068 .

Santhoshkumar , P. , and Sharma , K.K. ( 2002) Identiﬁ cation of a region in alcohol dehydrogenase that

binds to  -crystallin during chaperone action . Biochim. Biophys. Acta 1589 , 115 – 121 .

Santos , S.G. , Campbell , E.C. , Lynch , S., Wong , V. , Antoniou ,

A.N. , and Powis , S.J. ( 2007) Major histo-

compatibility complex class I–ERp57–tapasin interactions within the peptide-loading complex . J. Biol.

Chem. 282 ( 24) , 17587 – 17593 .

Santra , S., Wang , K., Tapec , R., and Tan , W. ( 2001) Development of novel dye-doped silica nanoparticles

for biomarker application . J. Biomed. Optics 6 , 160 – 166 .

Santuccione , A., Sytnyk , V. , Leshchyns ’ka,

I., and Schachner , M. ( 2005) Prion protein recruits its neuro-

nal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth . J. Cell Biol.

169 , 341 – 354 .

Sapsford , K.E. , Pons , T. , Medintz , I.L. , and Mattoussi , H. ( 2006) Biosensing with luminescent semicon-

ductor quantum dots . Sensors 6 , 925 – 953 .

Sashidhar , R.B. , Capoor , A.K. , and Ramana , P. ( 1994) Quantitation of e-amino group using amino acids

as reference standards by trinitrobenzene sulfonic acid . J. Immunol. Meth. 167 , 121 – 127 .

Sastry , L. , Alting-Mees , M., Huse , W.D. , Short , J.M. , Sorge , J.A. ,

Hay , B.N. , Janda , K.D. , Benkovic , S.J. ,

and Lerner , R.A. ( 1989) Cloning of the immunological repertoire in Escherichia coli for generation of

monoclonal catalytic antibodies: Construction of a heavy chain variable region-speciﬁ c cDNA library .

Proc. Natl. Acad. Sci. USA 86 , 5728 – 5732 .

Sasuga, Y. , Tani , T. , Hayashi, M., Yamakawa , H., Ohara, O., and Harada, Y. ( 2006) Development of a

microscopic platform for real-time monitoring of biomolecular interactions . Genome Res. 16 , 132– 139 .

Sato , N., Kobayashi , H., Saga , T. , Nakamoto , Y. , Ishimori , T. , Togashi , K., Fujibayashi ,

Y. , Konishi , J. ,

and Brechbiel , M.W. ( 2001) Tumor targeting and imaging of intraperitoneal tumors by use of anti-

sense oligo-DNA complexed with dendrimers and/or avidin in mice . Clin. Cancer Res. 7 , 3606 – 3612 .

Sato , S., and Nakao , M. ( 1981) Cross-linking of intact erythrocyte membrane with a newly synthesized

cleavable bifunctional reagent . J. Biochem. (Tokyo) 90 , 1177 .

Savage , D., Mattson , G., Desai , S., Nielander , G., Morgensen , S. , and Conklin , E. ( 1992) Avidin-Biotin

Chemistry: A Handbook . Pierce Chemical Company , Rockford, IL .

Sawin , K.E. , and Mitchison , T.J.

( 1991) Mitotic spindle assembly by two different pathways in vitro .

J. Cell Biol. 112 , 925

.

Sawyer , S.T. , Krantz , S.B. , and Luna , J. ( 1987) Identiﬁ cation of the receptor for erythropoietin by cross-

linking to Friend virus-infected erythroid cells . Proc. Natl. Acad. Sci. USA 84 , 3690 – 3694 .

Saxon , E. , and Bertozzi , C.R. ( 2000) Cell surface engineering by a modiﬁ ed Staudinger reaction . Science

287 , 2007 – 2010 .

References 1111

Saxon, E., and Carolyn R.B. (2003) Chemoselective ligation. US Patent No. 6,570,040.

Saxon, E., and Carolyn R.B. (2006) Chemoselective ligation. US Patent No. 7,122,703.

Saxon , E. , Armstrong , J.I. , and Bertozzi , C.R. ( 2000) A“ Traceless ” Staudinger ligation for the chemose-

lective synthesis of amide bonds . Org. Lett. 2 , 2141 – 2143 .

Sayre , L.M. , Smith , M.A. , and Perry , G. ( 2001) Chemistry and biochemistry of oxidative stress in neuro-

degenerative disease . Curr. Med. Chem. 8 , 721 – 738 .

Schepartz , A., and Cuenoud , B. ( 1990) Site-speciﬁ c cleavage of the protein calmodulin using a triﬂ uopera-

zine-based afﬁ nity reagent . J. Am. Chem. Soc. 112 , 3247 – 3249 .

Scherson, T. , Kreis, T.E. , Schlessinger , J., Littauer , U., Borisy , G.G., and Geiger , B.

( 1984) Dynamic interac-

tions of ﬂ uorescently labeled microtubule-associated proteins in living cells . J. Cell Biol. 99 , 425– 434 .

Schewale , J.G. , and Brew , K. ( 1982) Effects of Fe

3

binding on the microenvironments of individual

amino groups in human serum transferrin as determined by different kinetic labeling . J. Biol. Chem.

257 , 9406 .

Schiel , J.E. , Mallik , R., Soman , S., Joseph , K.S. , and Hage , D.S. ( 2006) Applications of silica supports in

afﬁ nity chromatography . J. Sep. Sci. 29 , 719 – 737 .

Schimitschek , E.J. , Trias , J.A. , Hammond , P.R. , and Atkins , R.L. ( 1974) Laser performance and stability

of ﬂ uorinated coumarin dyes . Opt. Comm. 11 , 352 .

Schlom , J. ( 1986) Basic principles and applications of monoclonal antibodies in the management of carci-

nomas . Cancer Res. 46 , 3225 .

Schmer , G.

( 1972) Hoppe-Seyler ’s Z . Physiol. Chem. 353

, 810 .

Schmidt, A., Kalkhof, S., Ihling, C., Schulz, D.M., Beck-Sickinger, A.G., Cooper, D.M.F., and Sinz, A.

(2005) Studying calmodulin/adenylyl cyclase 8 interaction using isotope-labeled cross-linkers and

FTICR mass spectrometry. Poster, Pierce Biotechnology web site.

Schmitt , M., Painter , R.G. , Jesaitis , A.J. , Preissner , K. , Sklar , L.A. , and Cochrane , C.G. ( 1983 )

Photoafﬁ nity labeling of the N-formyl peptide receptor binding site of intact human polymorphonu-

clear leukocytes . J. Biol. Chem. 258 , 649 – 654 .

Schnapp , K.A. , and Platz , M.S. ( 1993) A laser ﬂ ash photolysis study of di-, tri- and tetraﬂ uorinated phe-

nylnitrenes; Implications for photoafﬁ nity labeling . Bioconjugate Chem. 4 , 178 – 183 .

Schnapp , K.A. , Poe , R., Leyva , E.,

Soundararajan, N., and Platz , M.S. ( 1993) Exploratory photochemistry

of ﬂ uorinated aryl azides. Implications for the design of photoafﬁ nity labeling reagents . Bioconjugate

Chem.

4 , 172 – 177 .

Schneede , J. , and Ueland , P.M. ( 1992) Formation in an aqueous matrix and properties and chromato-

graphic behavior of 1-pyrenyldiazomethane derivatives of methylmalonic acid and other short-chain

dicarboxylic acids . Anal. Chem. 64 , 315 .

Schneider , C., Newman , R.A. , Sutherland , D.R. , Asser , U. , and Greaves , M.F. ( 1982) A 1 step puriﬁ cation

of membrane proteins using a high efﬁ ciency immuno matrix . J. Biol. Chem. 257 , 10766 – 10769 .

Schneider , L.V. , and Hall , M.P. ( 2005) Stable isotope methods for high-precision proteomics . Drug

Discov. Today 10

( 5) , 353 – 363 .

Schroeder , W.A. , Shelton , J.R. , and Robberson , B. ( 1967)

Modiﬁ cation of methionyl residues during ami-

noethylation . Biochim. Biophys. Acta 147 , 590 – 592 .

Schuberth , H.-J. et al . ( 1996) Biotinylation of cell surface MHC molecules: A complementary tool for the

study of MHC class II polymorphism in cattle . J. Immunol. Meth. 189 , 89 – 98 .

Schwartz , B.A. , and Gray , G.R. ( 1977) Proteins containing reductively aminated disaccharides. Synthesis

and chemical characterization . Arch. Biochem. Biophys. 181 , 542 – 549 .

Schwartz, D.A., Abrams, M.J., Giadomenico, C.M., and Zubieta, J.A. (1993) Certain pyridyl hydrazines

and hydrazides useful for protein labeling. US Patent No. 5,206,370.

Schwartz, D.A., Abrams, M.J., Giadomenico, C.M., and Zubieta, J.A. (1995) Protein labelling utilizing

certain pyridyl hydrazines, hydrazides and derivatives. US Patent No. 5,420,285.

Schwartz , W.E. , Smith , P.K. , and Royer ,

G.P. ( 1980) N-( -iodoethyl)triﬂ uoroacetamide: A new reagent for

the aminoethylation of thiol groups in proteins . Anal. Biochem. 106 , 43 – 48 .

1112 References

Schwinghamer , E.A. ( 1980) A method for improved lysis of gram-negative bacteria . FEMS Microbiol.

Lett. 7 , 157 – 162 .

Scopes , R. ( 1982) Protein Puriﬁ cation . Springer-Verlag , New York . p. 30

Scorilas , A., Bjartell , A., Lilja , H., Moller , C. , and Diamandis , E.P. ( 2000) Streptavidin–polyvinylamine

conjugates labeled with a europium chelate: Applications in immunoassay, immunohistochemistry, and

microarrays . Clin. Chem. 46 , 1450 – 1455 .

Scott Jr. , C.J., Goldmacher , V.S. , Lambert, J.M., Chari, R.V. , Bolender , S., Gauthier , M.N., and Blattler ,

W.A.

(1987) The antileukemic efﬁ cacy of an immunotoxin composed of a monoclonal anti-Thy-1 antibody

disulﬁ de linked to the ribosome-inactivating protein gelonin . Cancer Immunol. Immunother. 25 , 31 .

Scott , D.C. , Newton , S.M.C. , and Klebba , P.E.

( 2002) Surface loop motion in FepA . J. Bacteriol. 184 ,

4906 – 4911 .

Scouten, W. H. (1983) Solid Phase Biochemistry (W.H., Scouten, ed.), pp. 149–187. John Wiley and Sons,

New York.

Scouten , W.H. , and Van den Tweel , W. ( 1984) Chromophonic sulfonyl chloride agarose for immobilizing

bioligands . Annal. N.Y. Acad. Sci. 434 , 249 .

Sculimbrene , B.R. , and Imperiali , B. ( 2006) Lanthanide-binding tags as luminescent probes for studying

protein interactions . J. Am. Chem. Soc. 128 ( 22) , 7346 – 7352 .

Seela ,

F. , and Waldeck , S. ( 1975) Agarose linked adenosine and guanosine-5 -monophosphate; a new gen-

eral method for the coupling of ribonucleotides to polymers through their cis-diols . Nucleic Acids Res.

2 , 2343 – 2349 .

Segal , D.M. , and Hurwitz , E. ( 1976) Dimers and trimers of immunoglobulin G covalently cross-linked

with a bivalent afﬁ nity label .

Biochemistry 15 , 5253 .

Sela , M., and Hurwitz , E. ( 1987) Conjugates of antibodies with cytotoxic drugs .In Immunoconjugates:

Antibody Conjugates in Radioimaging and Therapy of Cancer (C.-W. Vogel, ed.) , p. 189 . Oxford

University Press , New York .

Seligsberger , L., and Sadlier , C. ( 1957) New developments in tanning with aldehydes . J. Am. Leather

Chem. Assoc. 52 ,2 .

Selvin ,

P.R. ( 2000) The renaissance of ﬂ uorescence resonance energy transfer . Nat. Struct. Biol. 7 (9) ,

730 – 734 .

Selvin , P.R. ( 2002) Principles and biophysical applications of luminescent lanthanide probes . Annu. Rev.

Biophys. Biomol. Struct. 31 , 275 – 302 .

Selvin , P.R. ( 2003) Lanthanide-labeled DNA .In Topics in Fluorescence Spectroscopy, (J. Lakowicz, ed.) ,

Vol. 7, pp. 177 – 212 . Kluwer Academic/Plenum , New York

.

Senozan , N. et al . ( 1981) Hemocyanin of the giant keyhold limpet, Megathura crenulata .In Invertebrate

Oxygen Binding Proteins: Structure, Active Sites, and Function ( J. Lamy , and J. Lamy , eds.) , pp. 703 – 717 .

Dekker , New York .

Senter , P.D. , Saulnier , M.G. , Schreiber , G.J. , Hirschberg , D.L. , Brown , J.P. , Hellstrom , I. , and Hellstrom , K.E.

(1988) Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide

phosphate . Proc. Natl. Acad. Sci. USA 85 , 4842 .

Severinov , K., and Muir , T.W. ( 1998) Expressed protein ligation, a novel method for studying protein–

protein interactions in transcription . J. Biol. Chem. 273 ( 26) , 16205 – 16209 .

Sgro , J. , Jacrot , B., and Chroboczek ,

J. ( 1986) Identiﬁ cation of regions of brome mosaic virus coat pro-

tein chemically cross-linked in situ to viral RNA . Eur. J. Biochem. 154 , 69 – 76 .

Shabarova , Z.A. ( 1988) Chemical development in the design of oligonucleotide probes for binding to

DNA and RNA . Biochimie 70 , 1323 – 1334 .

Shabarova , Z.A. , Ivanovskaya , M.G. , and Isaguliants , M.G. ( 1983) DNA-like duplexes with repetitions:

Efﬁ cient template-guided polycondensation of decadeoxyribonucleotide imidazolide . FEBS Lett. 154 ,

288 – 292 .

Shacter , E. ( 2000) Quantiﬁ cation and signiﬁ cance of protein oxidation in biological samples . Drug Metab.

Rev. 32 , 307 – 326 .

References 1113

Shaheen , S., Brabec , C.J. , Sariciftci , N.S. , Padinger , F. , Fromherz , T. , and Hummelen , J.C. ( 2001) 2.5%

efﬁ cient organic plastic solar cells . Appl. Phys. Lett. 78 , 841 – 846 .

Shaltiel , S. ( 1967) Thiolysis of some dinitrophenyl derivatives of amino acids . Biochem. Biophys. Res.

Comm. 29 , 178 .

Shanahan , M.F. , Wadzinski , B.E. , Lowndes , J.M. , and Ruoho , A.E. ( 1985) Photoafﬁ nity labeling of the

human erythrocyte monosaccharide transporter with an aryl azide derivative of

D-glucose . J. Biol.

Chem. 260 , 10897 – 10900 .

Shannon , L.M. , Kay , E. , and Lew , J.Y. ( 1966) Peroxidase isozymes from horseradish roots. I. Isolation

and physical properties . J. Biol. Chem. 241 , 2166 .

Shapiro , R. , and Weisgras , J.M. ( 1970) Bisulﬁ te-catalyzed transamination of cytosine and cytidine .

Biochem. Biophys. Res. Comm. 40 , 839 – 843 .

Shapiro , R., Braverman , B., Louis , J.B. , and Servis , R.E. ( 1973) Nucleic acid reactivity and conformation.

II. Reaction of cytosine and uracil with sodium bisulﬁ te . J. Biol. Chem. 248 , 4060 – 4064 .

Shapiro , R., DiFate ,

V. , and Welcher , M. ( 1974) Deamination of cytosine derivatives by bisulﬁ te.

Mechanism of the reaction

. J. Am. Chem. Soc. 96 , 906 – 912 .

Sharma , K.K. et al . ( 2000) Synthesis and characterization of a peptide identiﬁ ed as a functional element

in  -crystallin . J. Biol. Chem. 275 ( 6 ) , 3767 – 3771 .

Sharon , N. , and Lis , H. ( 1989) Lectins as cell recognition molecules . Science 246 , 227 – 234 .

Sharpless, B.K., Fokin, V., Rostovtsev, V.V., Green, L., and Himo, F. (2005) Copper-catalysed ligation of

azides and acetylenes. US Patent Application 2005/0222427 A1, published October 6, 2005, ﬁ led May

30, 2003; provisional application ﬁ led May 30, 2002.

Shechter , Y. , Mironchik , M., Rubinraut , S., Saul , A., Tsubery , H., and Fridkin ,

M. ( 2005) Albumin–insulin

conjugate releasing insulin slowly under physiological conditions: A new concept for long-acting

insulin . Bioconjugate Chem. 16 , 913 – 920 .

Sheehan , D.C. , and Hrapchak , B.B. ( 1980) Theory and Practice of Histotechnology , 2nd edn., Mosby ,

St. Louis, MO .

Sheehan , J.C. , and Hess , G.P. ( 1955) A new method of forming peptide bonds . J. Am. Chem. Soc. 77 ,

1067 – 1068 .

Sheehan , J.C. , and Hlavka , J.J. ( 1956) The use of water-soluble and basic carbodiimides in peptide syn-

thesis . J. Org. Chem. 21 , 439 – 441 .

Sheehan , J.C. , Cruickshank , P.A. , and Boshart , G.L. ( 1961) A convenient synthesis of water-soluble car-

bodiimides

. J. Org. Chem. 26 , 2525 – 2528 .

Sheehan , J.C. , Preston , J. , and Cruickshank

, P.A. ( 1965) A rapid synthesis of oligonucleotide derivatives

without isolation of intermediates . J. Am. Chem. Soc. 87 , 2492 – 2493 .

Shek , P.N. , and Heath , T.D. ( 1983) Immune response mediated by liposome-associated protein antigens.

III. Immunogenicity of bovine serum albumin covalently coupled to vesicle surface . Immunology

50 , 101 .

Shek , P.N. , and Sabiston , B.H. ( 1982a) Immune response mediated by liposome-associated protein

antigens. I. Potentiation of the plaque-forming cell response . Immunology 45 , 349 .

Shek , P.N. , and Sabiston , B.H. ( 1982b) Immune response mediated by liposome-associated protein anti-

gens. II. Comparison of the effectiveness of vesicle-entrapped and surface-associated antigens in immu-

nopotentiation . Immunology 47 , 627 .

Shephard , E.G. , DeBeer , F.C. , von Holt , C. , and Hapgood , J.P. ( 1988) The use of sulfosuccinimidyl-2-( p -

azidosalicylamido)-1,3-dithiopropionate as a cross-linking reagent to identify cell surface receptors .

Anal. Biochem. 168 , 306 – 313 .

Sherry , A.D. , Brown III , R.D. , Geraldes , C.F.C. , Koeng , S.H. , and Kuan , K.-T. ( 1989) Synthesis and char-

acterization of the gadolinium ( 3 ) complex of DOTA-propylamide: A model DOTA–protein conju-

gate . Inorg. Chem. 28 , 620 – 622 .

Shetty , J.K. , and Kinsella , J.E. ( 1980) Ready separation of proteins from nucleoprotein complexes by

reversible modiﬁ cation of lysine residues . Biochem. J. 191 , 269 – 272 .

1114 References

Shetty , K.J. , and Rao , M.S.N. ( 1978) Effect of succinylation on the oligomeric structure of arachin . Int.

J. Pept. Protein Res. 11 , 305 .

Shi , X., Bányai , I., Islam , M.T. , Lesniak , W. , Davis , D.Z. , Baker Jr. , J.R. , and Balogh , L.P. ( 2005)

Generational, skeletal and substitutional diversities in generation one poly(amidoamine) dendrimers .

Polymer 46 ( 9) , 3022 – 3034 .

Shi , X., Wang , S. , Sun , H., and Baker Jr. , J.R. ( 2007) Improved biocompatibility of surface functionalized

dendrimer-entrapped gold nanoparticles . Soft Matter 3 ,71 –

74 .

Shiao , D.D.F. , Lumry , R., and Rejender , S.

( 1972) Modiﬁ cation of protein properties by change in charge.

Succinylated chymotrypsinogen . Eur. J. Biochem. 29 , 377 .

Shih , L.B. , Goldenberg , D.M. , Xuan , H., Lu, H., Sharkey , R.M. , and Hall , T.C. ( 1991) Anthracycline

immunoconjugates prepared by a site-speciﬁ c linkage via an aminodextran intermediate carrier . Cancer

Res. 51 , 4192 – 4198 .

Shimisu , N., Nickimins , W.K. , and Shimizu , Y. ( 1980) A cytotoxic epidermal growth factor cross-linked

to diphtheria toxin A-fragment . FEBS Lett. 118 , 274 .

Shimkus , M.,

Levy , J. , and Herman , T. ( 1985) A chemically cleavable biotinylated nucleotide: Usefulness

in the recovery of protein–DNA complexes from avidin afﬁ nity columns . Proc. Natl. Acad. Sci. USA

82 , 2593 – 2597 .

Shimomura , S., and Fukui , T. ( 1978)

Characterization of the pyridoxal phosphate site in glycogen phos-

phorylase b from rabbit muscle . Biochemistry 17 , 5359 .

Shivdasani , R.A. , and Thomas , D.W. ( 1988) Molecular associations of IA antigens after T–B cell interac-

tions . J. Immunol. 141 , 1252 – 1260 .

Shukla , S., Wu , G., Chatterjee , M., Yang , W. , Sekido , M., Diop , L.A. , Muller , R. , Sudimack , J.J.

, Lee , R.J. ,

Barth, R.F. , and Tjarks , W. ( 2003) Synthesis and biological evaluation of folate receptor-targeted boro-

nated PAMAM dendrimers as potential agents for neutron capture therapy . Bioconjugate Chem. 14 ,

158 – 167 .

Sia , C.L. , and Horecker , B.L. ( 1968) Dissociation of protein subunits by maleylation . Biochem. Biophys.

Res. Comm. 31 , 731 – 737 .

Siezen , R.J. , Bindels , J.C. , and Hoenders , H.J. ( 1980) The quaternary structure of bovine a-crystallin.

Chemical cross-linking with bifunctional imido esters . Eur. J. Biochem. 107 , 243 – 249 .

Silman , H.I. , Albu-Weissenberg , M., and Katchalski , E. ( 1966) Some water-insoluble papain derivatives .

Biopolymers 4

, 441 – 448 .

Silva , S.S. , Ferreira , R.A.S. , Fu, L., Carlos , L.D. , Mano , J.F. , Reis , R.L. , and Rocha , J. ( 2005) Functional

nanostructured chitosan–siloxane hybrids . J. Mater. Chem. 15 , 3952 – 3961 .

Silvius , J.R. , Leventis , R. , Brown , P.M. , and Zuchermann ,

M. ( 1987) Novel ﬂ uorescent phospholipids for

assays of lipid mixing between membranes . Biochemistry 26 , 4279 – 4287 .

Simon , J.R. , and Taylor , D.L. ( 1988) Preparation of a ﬂ uorescent analog: Acetamidoﬂ uoresceinyl labeled

dictyostelium discoideum a-actin .In Methods in Enzymology,

(R.B. Vallee , ed.) , Vol. 134, p. 47 .

Academic Press , San Diego .

Simon , S.R. , and Konigsberg , W.H. ( 1966) Chemical modiﬁ cation of hemoglobins: A study of conforma-

tion restraint by internal bridging . Proc. Natl. Acad. Sci. USA 56 , 749 .

Simons , M., Friedrichson , T. , Schulz , J.B. , Pitto , M., Masserini , M., and Kurzchalia , T.V. ( 1999)

Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains

in living cells . Mol. Biol. Cell 10 , 3187 – 3196 .

Singer ,

J.M. , and Plotz , C.M. ( 1956) The latex ﬁ xation test. I. Application to the serologic diagnosis of

rheumatoid arthritis . Am. J. Med. 21 , 888 .

Singer ,

S.J. , Fothergill , J.E. , and Shainoff , J.R. ( 1960) A general method for the isolation of antibodies .

J. Am. Chem. Soc. 82 , 565 .

Singh , P. ( 1998) Terminal groups in starburst dendrimers: Activation and reactions with proteins .

Bioconjugate Chem. 9 ,54 – 63 .

References 1115

Singh , R. et al . ( 1996) Formation of N-substituted 2-iminothiolanes when amino groups in proteins and

peptides are modiﬁ ed by 2-iminothiolane . Anal. Biochem. 236 ( 1 ) , 114 – 125 .

Singh , R., Barden , A., Mori , T. , and Beilin , L. ( 2001) Advanced glycation end-products: A review .

Diabetologia 44 (2 ) , 129 – 146 .

Singh , R., Pantarotto , D., Lacerda , L., Pastorin , G., Klumpp , C., Prato , M., Bianco , A., and Kostarelos ,

K. ( 2006) Tissue biodistribution and blood clearance rates of intravenously administered carbon nano-

tube radiotracers

. Proc. Natl. Acad. Sci. USA 103 , 3357 – 3362 .

Singh ,

V. , Sairam , M.R. , Bhargavi , G.N. , and Akhras , R.G. ( 1989) Hormonotoxins: Preparation and

characterization of ovine luteinizing hormone–gelonin conjugate . J. Biol. Chem. 264 , 3089 – 3095 .

Singh, V. , Mavila, A.K., and Kar , S.K. ( 1993) Comparison of the cytotoxic effect of hormonotoxins prepared

with the use of heterobifunctional cross-linking agents N-succinimidyl 3-(2-pyridyldithio)propionate and

N-succinimidyl 6-[3-(2-pyridyldithio)propionamido]-hexanoate . Bioconjugate Chem. 4 , 473– 482 .

Singhal , A., and Gupta , C.M. ( 1986) Antibody-mediated targeting of liposomes to red cells in vivo . FEBS

Lett. 201 , 321 .

Singhal , R.P.

, Bajaj , R.K. , Buess , G.M. , Smoll , D.B. , and Vakharia , V.N. ( 1980) Reversed-phase boro-

nate chromatography for the separation of O-methylribose nucleosides and aminoacyl-tRNAs . Anal.

Biochem. 109 ,1 – 11

.

Sinz , A. ( 2003) Chemical cross-linking and mass spectrometry for mapping three-dimensional structures

of proteins and protein complexes . J. Mass Spectrom. 38 , 1225 – 1237 .

Sinz , A. ( 2006) Chemical cross-linking and mass spectrometry to map three-dimensional protein struc-

tures and protein–protein interactions . Mass Spectrom. Rev. 25 , 663 – 682 .

Sinz , A., Kalkhof , S., and Ihling , C. ( 2005) Mapping protein interfaces by a trifunctional cross-linker

combined with MALDI-TOF and ESI-FTICR mass spectrometry . J. Am. Soc. Mass Spectrom. 16 ( 12) ,

1921 – 1931 .

Sipe , D.M. , Jesurum , A., and Murphy , R.F. ( 1991) Absence of Na



, K



-ATPase regulation of endosomal

acidiﬁ cation in K562 erythroleukemia cells . J. Biol. Chem. 266 , 3469 .

Sippel , T.O. ( 1981) New ﬂ uorochromes for thiols: Maleimide and iodoacetamide derivatives of 3-phenyl-

coumarin ﬂ uorophore . J. Histochem. Cytochem. 29 , 314 .

Siuzdak, G. (2006) The expanding role of mass spectrometry in biotechnology, 2nd edn., MCC Press,

ISBN-13: 978-0974245126.

Sivakoff , S.I. , and Janes , C.J. ( 1988) Automated high performance gel-ﬁ ltration chromatography

(HPGFC) processing of avidin coupled b-galactosidase . Biochromatography 3 , 62 – 68 .

Sivaraman , N., Srinivasan , T. , Vasudeva Rao , P. , and Natarajan , R. ( 2001) QSPR modeling for solubility

of fullerene (C60) in organic solvents . J. Chem. Inf. Comput. Sci. 41 , 1067 – 1074 .

Skare , J.T. , Ahmer , B.M. , Seachord ,

C.L. , Darveau , R.P. , and Postle ,

K. ( 1993) Energy transduction

between membranes. TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to

the outer membrane receptor FepA . J. Biol. Chem. 268 , 16302 – 16308 .

Skold , S.-E. ( 1983) Chemical crosslinking of elongation factor G to the 23S RNA in 70S ribosomes from

Escherichia coli . Nucleic Acids Res. 11 , 4923 .

Slaughter , T.F. , Achyuthan , K.E. , Lai , T.-S. , and Greenberg , C.S. ( 1992) A microtiter plate transglutami-

nase assay utilizing 5-(biotinamido)pentylamine as substrate . Anal. Biochem. 205 ,1 – 6 .

Slinkin , M.A. , Klibanov , A.L. , Khaw , B.A. , and Torchilin , V. P. ( 1990) Succinylated polylysine as a possi-

ble link between an antibody molecule and deferoxamine . Bioconjugate Chem. 1

, 291 – 295 .

Slinkin , M.A. , Klibanov ,

A.L. , and Torchilin , V. P. ( 1991) Terminal-modiﬁ ed polylysine-based chelating

polymers: Highly efﬁ cient coupling to antibody with minimal loss in immunoreactivity . Bioconjugate

Chem. 2 , 342 – 348 .

Slomkowski , S., Miksa , B., Chehimi , M.M. , Delamar , M., Cabet-Deliry , M., Majoral , J.P. , and Caminade ,

A.-M. ( 1999) Inorganic–organic systems with tailored properties controlled on molecular, macromo-

lecular and microscopic level . React. Funct. Polym. 41 , 45 – 57 .

1116 References

Slot , J.W. , and Geuze , H.J. ( 1984) Cold markers for single and double immunolabeling of ultrathin cryo-

sections .In Immunolabeling for Electron Microscopy (J.M. Polak , and I.M. Varndess, eds.) , p. 139 .

Elsevier , New York .

Smith , C.H. , and Barker , J.N.W.N. ( 2006) Psoriasis and its management . BMJ 333 , 380 – 384 .

Smith , D.F. , Zopf , D.A. , and Ginsburg , V. ( 1978) Carbohydrate antigens: Coupling of oligosacchanide

phenethylamine-isothiocyanate derivatives to bovine serum albumin .In Methods in Enzymology,

(V. Ginsburg, ed.) , Vol. 50, pp. 169 – 171 . Academic Press , New York .

Smith , L.M. , Fung ,

S., Hunkapiller , M.W. , Hunkapiller , T.J. , and Hood , L.E. ( 1985) The synthesis of oli-

gonucleotides containing an aliphatic amino group at the 5

 terminus: Synthesis of ﬂ uorescent DNA

primers for use in DNA sequence analysis . Nucleic Acids Res. 13 , 2399 – 2412 .

Smith , M.B. , and March , J. ( 2007) March ’s Advanced Organic Chemistry: Reactions, Mechanisms, and

Structure , 6th edn., John Wiley and Sons, Inc. , Hobokan, New Jersey .

Smith , P.K. , Krohn , R.I. , Hermanson , C.T. , Malhia , A.K. , Gartner , F.H. , Provenzano , M.D. , Fujimoto , E.K. ,

Goeke, N.M. , Olson , B.J. , and Klenk , D.C. ( 1985) Measurement of protein using bicinchoninic acid

.

Anal. Biochem. 150 , 76 – 85 .

Smith , R.A.G. , and Knowles , J.R. ( 1973) Aryldiazinines. Potential reagents for photolabeling of biologi-

cal receptor sites . J. Am. Chem. Soc. 95 , 5072 –

5073 .

Smith , R.J. , Capaldi , R.A. , Muchmone , D., and Dahlquist , F. ( 1978) Cross-linking of ubiquinone cytoch-

nome c reductase (complex III) with periodate-cleavable bifunctional reagents . Biochemistry 17 ,

3719 – 3723 .

Smyth , D.G. ( 1967) Acetylation of amino and tyrosine hydroxyl groups . J. Biol. Chem. 242 , 1592 – 1598 .

Smyth , D.G. , Blumenfeld , O.O. , and Konigsberg , W. ( 1964) Reaction of N

-ethylmaleimide with peptides

and amino acids . Biochem. J. 91 , 589 .

Smyth , D.G. , Nagamatsu , A., and Fruton , J.S. ( 1960) Reactions of N-ethylmaleimide . J. Am. Chem. Soc.

82 , 4600 .

Snyder , B. , and

Hammes , G.G. ( 1984) Structural mapping of chloroplast coupling factor . Biochemistry

23 , 5787 – 5795 .

Snyder , B. , and Hammes , G.G. ( 1985) Structural organization of chloroplast coupling factor . Biochemistry

24 , 2324 – 2331 .

Soellner , M.B. , Nilsson , B.L. , and Raines , R.T. ( 2002) Staudinger ligation of a-azido acids retains stereo-

chemistry

. J. Org. Chem. 67 , 4993 – 4996 .

Soellner , M.B. , Dickson , K.A. , Nilsson , B.L. , and Raines , R.T. ( 2003) Site-speciﬁ c protein immobilization

by Staudinger ligation . J. Am. Chem. Soc. 125 , 11790 – 11791 .

Soini , E. , and Kojola , H. ( 1983)

Time-resolved ﬂ uorometer for lanthanide chelates—A new generation of

monisotopic immunoassays . Clin. Chem. 29 , 65 – 68 .

Soini , E., and Lövgren , T. ( 1987) Time-resolved ﬂ uorescence of lanthanide probes and applications in bio-

technology . CRC Crit. Rev. Anal. Chem. 18 , 104 – 154 .

Soini , E. , Hemmila , I. , and

Dahlen, P. ( 1990) Time-resolved ﬂ uorescence in biospeciﬁ c assays [Review] .

Ann. Biol. Clin. 48 , 567 – 571 .

Sokolovsky , M., Riordan , J.F. , and Vallee , B.L. ( 1967) Conversion of 3-nitrotyrosine to 3-aminotyrosine

in peptides and proteins . Biochem. Biophys. Res. Comm. 27 , 20 .

Solomon , S.R. , Mielke , S., Savani , B.N. , Montero , A., Wisch , L., Childs , R., Hensel ,

N., Schindler , J. ,

Ghetie , V. , Leitman , S.F. , Mai , T. , Carter , C.S. , Kurlander , R., Read , E.J. , Vitetta , E.S. , and Barrett , A.J.

(2005) Selective depletion of alloreactive donor lymphocytes: A novel method to reduce the severity of

graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation .

Blood 106 , 1123 – 1129 .

Sorensen (1993) Method for isolation and puriﬁ cation of enzyme–antibody conjugates. US Patent No.

5,266,686.

Sorenson , P. , Farber , N.M. , and Krystal , G. ( 1986) Identiﬁ cation of the interleukin-3 receptor using an

iodinatable, cleavable, photoreactive cross-linking agent . J. Biol. Chem. 261 , 9094 – 9097 .

References 1117

Soundararajan , N., Liu , S.H. , Soundararajan , S. , and Platz , M.S. ( 1993) Synthesis and binding of new

polyﬂ uoninated aryl azides to a-chymotrypsin. New reagents for photoafﬁ nity labeling . Bioconjugate

Chem. 4 , 256 – 261 .

Souza , E.D. , Ginsberg , M.H. , Lam , S., and Plow , E.F. ( 1988) Chemical cross-linking of arginylglycyl-

aspartic acid peptides to an adhesion receptor on platelets . J. Biol. Chem. 263 , 3943 – 3951 .

Spangler , C.W. , Spangler , B.D. , Tarter , E.S. , and Suo , Z. ( 2004) Design and synthesis of dendritic tethers

for the immobilization of antibodies for the detection of class A bioterror pathogens . Poly. Preprints

45 ( 1) , 524 .

Spasic , D., Raemaekers ,

T. , Dillen , K., Declerck , I. , Baert , V. , Serneels , L. , Füllekrug , J. , and Annaert , W.

( 2007 ) Rer1p competes with APH-1 for binding to nicastrin and regulates–secretase complex assembly

in the early secretory pathway . J. Cell Biol. 176 , 629 – 640 .

Speers , A.E. , and Cravatt , B.F. ( 2004a) Chemical strategies for activity-based proteomics . Chem. Bio.

Chem. 5 , 41 – 47 .

Speers , A.E. , and Cravatt , B.F. ( 2004b) Proﬁ ling enzyme activities in vivo using click chemistry methods .

Chem. Biol. 11 , 535 – 546 .

Spiegel ,

S., Skutelsky , E. , Bayer , E.A. , and Wilchek ,

M. ( 1982) A novel approach for the topographical

localization of glycolipids on the cell surface . Biochim. Biophys. Acta 687 , 27 – 34 .

Spiegel , S., Wilchek , M., and Fishman , P.H. ( 1983) Fluorescent labeling of cell surface glycoconjugates

with Lucifer Yellow CH . Biochem. Biophys. Res. Comm. 112 , 872 – 877 .

Spiegel , S., Yamada , K.M. , Hom , B.E. , Moss , J. , and Fishman , P.H. ( 1985) Fluorescent gangliosides as

probes for the retention and organization of ﬁ bronectin by ganglioside-deﬁ cient mouse cells . J. Cell

Biol. 100 , 721 – 726 .

Springer, A.L., Gall, A.S., Hughes, K.A., Kaiser, R.J., Li, G., Lucas, D.D., Lund., K.P., Spicer, D.A., Wiley, J.P.

(2002) Afﬁ nity-based immobilization tools for functional genomics. Presented at Transcriptome 2002:

From Functional to Systems Biology, Seattle, WA, March 10–13, 2002.

Springer , A.L. , Gall , A.S. , Hughes , K.A. , Kaiser , R.J. , Li , G., and Lund

, K.P. ( 2003) Salicylhydroxamic

acid functionalized afﬁ nity membranes for speciﬁ c immobilization of proteins and oligonucleotides .

J Biomol. Tech. 14 ( 3) , 183 – 190 .

Srikrishna , G., Toomre , D.K. , Manzi , A., Panneerselvam , K., Freeze , H.H. , Varki , A., and Varki , N.M.

( 2001 ) A novel anionic modiﬁ cation of N-glycans on mammalian endothelial cells is recognized by

activated neutrophils and modulates acute inﬂ ammatory responses . J. Immunol. 166 , 624 – 632 .

Srikant , P. , Singh , A.K.

, McElhanon , J.R. , and Dentinger , P.M. ( 2004) Dendrimer-activated surfaces for

high density and high activity protein chip applications . Langmuir 20 ( 15) , 6075 – 6079 .

Srinivasachar , K., and Neville

Jr. , D.M. ( 1989) New protein cross-linking reagents that are cleaved by

mild acid . Biochemistry 28 , 2501 .

Stadtman, E.R. ( 1992) Protein oxidation and aging . Science 257 , 1220 .

Stadtman , E.R. , and Levine , R.L. ( 2000) Protein oxidation . Ann. NY. Acad. Sci. 899 , 191 – 208 .

Stahlberg , T. , Markela , E., Mikola , H., Mottram ,

P. , and Hemmila , I. ( 1993) Europium and samarium in

time-resolved ﬂ uoroimmunoassays . American Laboratory December , 15 – 20 .

Staros , J.V. ( 1982) N-hydroxysulfosuccinimide active esters: Bis ( N-hydroxysulfosuccinimide) esters of

two dicarboxylic acids are hydrophilic, membrane impermeant, protein cross-linkers . Biochemistry 21 ,

3950 – 3955 .

Staros , J.V. ( 1988) Membrane-impermeant cross-linking reagents: Probes of the structure and dynamics

of membrane proteins . Acc. Chem. Res. 21 , 435 – 441 .

Staros , J.V. , and Kakkad , B.P. ( 1983) Cross-linking and chymotryptic digestion of the extracytoplasmic

domain of the anion exchange channel in intact human erythrocytes . J. Membr. Biol. 74 , 247 – 254 .

Staros , J.V. , Bayley , H., Standring , D.N.

, and Knowles , J.R. ( 1978) Reduction of aryl azides by thiols:

Implication for the use of photoafﬁ nity reagents . Biochem. Biophys. Res. Comm. 80 , 568 .

Staros , J.V. , Wright , R.W. , and Swinghe , D.M. ( 1986) Enhancement by N-hydroxysulfosuccinimide of

water-soluble carbodiimide-mediated coupling reactions . Anal. Biochem. 156 , 220 – 222 .

1118 References

Staros , J.V. , Lee , W. T. , and Conrad , D.H. ( 1987) Membrane-impermeant cross-linking reagents:

Application to the study of the cell surface receptor for IgE .In Methods in Enzymology, (G. Di Sabato,

ed.) , Vol. 150, pp. 503 – 512 . Academic Press , Orlando, FL .

Staudinger , H., and Meyer , J. ( 1919) Über neue organische phosphorverbindungen III. Phosphinmethyl-

enderivate und phosphinimine . Helv. Chim. Acta 2 , 635 – 646 .

Stauffer , D.A. , and Karlin , A. ( 1994) Electrostatic potential of the acetylcholine binding sites in the

nicotinic receptor probed by reaction of binding-site cysteines with charged methanethiosulfonates .

Biochemistry 33 , 6840 – 6849 .

Stears , R.L. , Getts , R.C. , and Gullans , S.R. ( 2000)

A novel, sensitive detection system for high-density

microarrays using dendrimer technology . Physiol. Genomics 3 , 93 – 99 .

Steel ,

G.J. , Fullerton , D.M. , Tyson , J.R. , and Stirling , C.J. ( 2004) Coordinated activation of Hsp70 chap-

erones . Science 303 , 98 – 101 .

Steer , C.J. , and Ashwell , G. ( 1986) Hepatic membrane receptors for glycoproteins . Prog. Liver Dis. 8 ,

99 – 123 .

Sternberger , L.A. ( 1986) Immunocytochemistry . Wiley , New York .

Stewart , J.M. , and Young , J.D. ( 1984) Solid Phase Peptide Synthesis , 2nd Edn. Pierce Chemical Company ,

Rockford, IL .

p. 31

Stewart , W. W. ( 1978) Functional connections between cells as revealed by dye-coupling with a highly

ﬂ uorescent naphthahimide tracer . Cell 14 , 741 .

Stewart , W. W. ( 1981a) Lucifer dyes—Highly ﬂ uorescent dyes for biological tracing

. Nature (London)

292 , 17 .

Stewart, W. W. ( 1981b) Synthesis of 3,6-disulfonate 4-aminonaphthalimides . J. Am. Chem. Soc. 103 , 7615 .

Stickel , S.K. , and Wang , Y.-L. ( 1988) Synthetic peptide GRGDS induces dissociation of alpha-actin and

vinculin from the sites of focal contacts . J. Cell Biol. 107 , 1231 .

Stirpe , F. , Olsnes , S., and Pihl , A. ( 1980) Gelonin, a new inhibitor of protein synthesis, nontoxic to intact

cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavahin A . J. Biol.

Chem. 255 , 6947 –

6953 .

Stöber , W. , Fink , A., and Bohn , E.J. ( 1968) Controlled growth of monodisperse silica spheres in the

micron size range . Colloid Interface Sci. 26 , 62 – 69 .

Stocking , E.M. , and Williams , R.M. ( 2002) Chemistry and biology of biosynthetic Diels–Alder reactions .

Angew. Chem. Int. Ed. Engl.

42 ( 27) , 3078 – 3115 .

Stolowitz, M.L. (1997) Phenylboronic acid complexes for bioconjugate preparation. US Patent No.

5,594,111.

Stolowitz , M.L. , Ahlem , C. , Hughes , K.A. , Kaiser , R.J. , Kesicki , E.A. , Li, G., Lund , K.P. , Torkelson , S.M. ,

and Wiley , J.P. ( 2001)

Phenylboronic acid–salicylhydroxamic acid bioconjugates. 1. A novel boronic

acid complex for protein immobilization . Bioconjugate Chem. 12 , 229 – 239 .

Straubinger , R.M. , Lopez , N.G. , Debs , R.J. , Hong , K., and Papahajopoulos , D. ( 1988) Liposome-based

therapy of human ovarian cancer: Parameters determining potency of negatively charged and anti-

body-targeted liposomes . Cancer Res. 48 , 5237 – 5245 .

Strickland , E., Hardin , E.K. , Shannon ,

L.M. , and Horwitz , J. ( 1968) Peroxidase isoenzymes from horse-

radish roots. III. Circular dichroism of isoenzymes and apoisoenzymes . J. Biol. Chem. 243 , 3560 .

Striebel , H.M. , Birch-Hirschfeld , E., Egerer , R., Foldes-Papp , Z., Tilz , G.P. , and Stelzner , A.

( 2004)

Enhancing sensitivity of human herpes virus diagnosis with DNA microarrays using dendrimers . Exp.

Mol. Pathol. 77 ,89 – 97 .

Strottmann , J.M. , Robinson Jr. , J.B. , and Stehlwagen , E. ( 1983) Advantages of preelectrophoretic conju-

gation of polypeptides with ﬂ uorescent dyes . Anal. Biochem. 132 , 334 – 337 .

Stuchbury , T. , Shipton , M., Norris , R., Malthouse , J.P.G. , and Brocklehurst , K. ( 1975) Reporter groups

delivery system with both absolute and selective speciﬁ city for thiol groups and an improved ﬂ uores-

cent probe containing the 7-nitrobenzo-2-oxa-1,3-diazole moiety

. Biochem. J. 151 , 417 – 432 .

References 1119

Stump , R.F. , Pfeiffer , J.R. , Schneebeck , M.C. , Seagrave , J.C. , and Oliver , J.M. ( 1989) Mapping gold-

labeled receptors on cell surfaces by backscattered electron imaging and digital image analysis: Studies

of the IgE receptor on mast cells . Am. J. Anat. 185 , 128 – 141 .

Subramanian , R., and Meares , C.F. ( 1991) Bifunctional chelating agents for radiometal-labeled mono-

clonal antibodies .In Cancer Imaging with Radiolabeled Antibodies (D.M. Coldenberg, ed.) , pp. 183 –

199 . Kluwer , Boston, MA .

Suchanek , M., Radzikowska , A., and Thiele , C. ( 2005) Photo-leucine and photo-methionine allow identi-

ﬁ cation of protein–protein interactions in living cells . Nat. Meth. 2 (4 ) , 261 – 267 .

Sulkowski , E. ( 1985) Puriﬁ cation of proteins by IMAC . Trends Biotechnol. 3 ,1 – 7 .

Sun , J.-S. , Francois , J.-C. , Lavery , R., Saison-Behmoaras , T. , Montenay-Garestier , T. , Thuong , N.T. , and

Helene , C. ( 1988) Sequence-targeted cleavage of nucleic acids by oligo-a-thymidylate–phenanthro-

line conjugates: Parallel and antiparallel double helices are formed with DNA and RNA, respectively .

Biochemistry 27 , 6039 – 6045 .

Sun , M.M.C. , Beam , K.S. , Cerveny , C.G. , Hamblett , K.J. , Blackmore , R.S. , Torgov , M.Y. , Handley , F.

G.M. , Ihle , N.C. , Senter , P.D. , and Alley ,

S.C. ( 2005) Reduction–alkylation strategies for the modiﬁ ca-

tion of speciﬁ c monoclonal antibody disulﬁ des . Bioconjugate Chem. 16 , 1282

– 1290 .

Sun , T.T. , Bollen , A., Kahan , L., and Traut , R.R. ( 1974) Topography of ribosomal proteins of the

Escherichia coli 30S subunit as studied with the reversible cross-linking reagent methyl 4-mercaptobu-

tyrimidate . Biochemistry 13 , 2334 – 2340 .

Sun , X.-L. , Stabler , C.L. , Cazalis , C.S. , and Chaikof , E.L. ( 2006) Carbohydrate and protein immobiliza-

tion onto solid surfaces by sequential diels–alder and azide–alkyne cycloadditions . Bioconjugate Chem.

17 , 52 – 57 .

Sundberg , L., and Porath , J. ( 1974) Preparation of adsorbents for biospeciﬁ c afﬁ nity chromatography.

I. Attachment of group containing ligands to insoluble polymers by means of bufunctional oxiranes .

J. Chromatogr.

90 , 87 – 98 .

Susaki , H., Suzuki , K. , Ikeda , M., Yamada ,

H., and Watanabe , H.K. ( 1998) Renal drug targeting using a

vector “ alkylglycoside ” . Chem. Pharm. Bull. 46 , 1530 – 1537 .

Suter , M., and Butler , J.E. ( 1986) The immunochemistry of sandwich ELISAs. II. A novel system prevents

the denaturation of capture antibodies . Immunol. Lett. 13 , 313 – 316 .

Sutoh , K. , and Hiratsuka , T. ( 1988) Spatial proximity of the glycine-rich loop and the SH2 thiol in

myosin subfragment 1 . Biochemistry 27 ( 8) , 2964 – 2969 .

Sutoh , K. ,

Yamamoto , K., and Wakabayashi , T. ( 1984) Electron microscopic visualization of the SH1

thiol of myosin by the use of an avidin–biotin system . J. Mol. Biol. 178 , 323 – 339 .

Swali , V. , Wells , N.J. , Langley , G.J.

, and Bradley , M. ( 1997) Solid-phase dendrimer synthesis and

the generation of super-high-loading resin beads for combinatorial chemistry . J. Org. Chem. 62 ,

4902 – 4903 .

Swanson , J., Burke , E., and Silverstein , S.C. ( 1987) Tubular lysosomes accompany stimulated pinocytosis

in macrophages . J. Cell Biol. 104 , 1217 .

Swanson , S.J. , Lin , B.-F. , Mullenix , M.C. , and Mortensen , R.F. ( 1991) A synthetic peptide correspond-

ing to the phosphorylcholine (PC)-binding region of human C-reactive protein possesses the TEPC-15

myeloma PC-idiotype

. J. Immunol. 146 , 1596 – 1601 .

Swanton , E., Holland , A., High , S., and Woodman , P. ( 2005) Disease-associated mutations cause pre-

mature oligomerization of myelin proteolipid protein in the endoplasmic reticulum . PNAS 102 ,

4342 – 4347 .

Sweeley ,

C.C. , and Nunez , H.A. ( 1985) Structural analysis of glycoconjugates by mass spectrometry and

nuclear magnetic resonance spectroscopy . Annu. Rev. Biochem. 54 , 765 – 801 .

Sykaluk, L. (1994) unpublished data, Pierce Chemical.

Szabo , J. , Kruger , S.R. , and Beall , G.N. ( 1989) Detection of cells producing anti-idiotypic antibody to

thyroid stimulating hormone-reactive antibodies . Immunol. Invest. 18 , 879 – 884 .

Hermanson G. Bioconjugate Techniques, Second Edition

Подождите немного. Документ загружается.