Michael Palmer, Department of Chemistry, University of Waterloo,
Canada
Third edition, January 2007. 145 pages.
About these notes
These course notes have been assembled during several classes I taught on Biochemical Pharmacology. I welcome corrections and suggestions for improvement.
Contents
About these notes
Chapter1.
Introduction
What are drugs?
Drugs and drug target molecules
Drug molecules may or may not have physiological counterparts
Synthetic drugs may exceed the corresponding physiological agonists in selectivity
Metabolism of physiological mediators and of drugs
Strategies of drug development
Chapter2.
Pharmacokinetics
Drug application and uptake
Oral drug application
Intravenous drug application
Other routes of drug applicaton
Drug distribution
Vascular permeability; the blood brain barrier .
Drug hydrophobicity and permeation across membranes
Third edition, January 2007. 145 pages.
About these notes
These course notes have been assembled during several classes I taught on Biochemical Pharmacology. I welcome corrections and suggestions for improvement.
Contents
About these notes
Chapter1.
Introduction
What are drugs?
Drugs and drug target molecules
Drug molecules may or may not have physiological counterparts
Synthetic drugs may exceed the corresponding physiological agonists in selectivity
Metabolism of physiological mediators and of drugs
Strategies of drug development
Chapter2.
Pharmacokinetics
Drug application and uptake
Oral drug application
Intravenous drug application
Other routes of drug applicaton
Drug distribution
Vascular permeability; the blood brain barrier .
Drug hydrophobicity and permeation across membranes