the return of Columbus in that year, is a matter still debated by
the well informed, and not to be settled here.
Certain facts support the theory of an indigenous European
origin. On July 25, 1463, a prostitute testified in a court at Dijon
that she had dissuaded an unwelcome suitor by telling him that she had
le gros mal - not further described in the record. `051930 On March
25, 1494, the town crier of Paris was directed to order from the
city all persons afflicted with la grosse verole. `051931 We do
not know what this "great pox" was; it may have been syphilis. Late in
1494 a French army invaded Italy; on February 21, 1495, it Occupied
Naples; soon afterward a malady became rampant there, which the
Italians called il morbo gallico, "the French disease," alleging
that the French had brought it into Italy. Many of the French soldiers
were infected with it; when they returned to France, in October, 1495,
they scattered the disease among the people; in France, therefore,
it was called le mal de Naples, on the assumption that the French
army had contracted it there. On August 7, 1495, two months before the
return of the French army from Italy, the Emperor Maximilian issued an
edict in which mention was made of malum francicum; obviously this
"French disease" could not be ascribed to the French army not yet
returned from Italy. From 1500 on, the term morbus gallicus was used
throughout Europe to mean syphilis. `051932 We may conclude that there
are suggestions, but no convincing evidence, that syphilis existed
in Europe before 1493.
The case for an American origin is based upon a report written
between 1504 and 1506 (but not published till 1539) by a Spanish
physician, Ruy Diaz de l'Isla. He relates that on the return voyage of
Columbus the pilot of the admiral's vessel was attacked by a severe
fever, accompanied with frightful skin eruptions, and adds that he
himself, at Barcelona, had treated sailors infected with this new
disease, which, he says, had never been known there before. He
identified it with what Europe was calling morbus gallicus, and
contended that the infection had been brought from America. `051933
Columbus, on his first return from the West Indies, reached Palos,
Spain, on March 15, 1493. In that same month Pintor, physician to
Alexander VI, noted the first appearance of the morbus gallicus in
Rome. `051934 Almost two years elapsed between the return of