Humana Press, 2012. - 340 p. - Increasing interest in mitochondrial
bioenergetics is being driven by the impact of drug and
environmental chemical-induced disturbances of mitochondrial
function as well as hereditary deficiencies and the progressive
deterioration of bioenergetic performance with age. These
initiatives have fostered the investigation of genetic and
environmental influences on bioenergetics. In Mitochondrial
Bioenergetics: Methods and Protocols, researchers in the field
detail the practical principles and assays designed to derive
quantitative assessment of each set of parameters that reflect
different aspects of mitochondrial bioenergetics. Written in the
highly successful Methods in Molecular Biology™ series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and key tips on troubleshooting
and avoiding known pitfalls Authoritative and practical,
Mitochondrial Bioenergetics: Methods and Protocols helps elevate
the quality and rate of investigative discoveries regarding disease
states associated with environmental or genetic influences on
mitochondrial bioenergetics.