Warren S., Wyatt P. Organic Synthesis: The Disconnection Approach

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добавлен 10 апреля 2011 г.

2nd ed. Wiley. 2008. 342 p.
The Disconnection Approach
Basic Principles: Synthesis: Synthons and Reagent Synthesis of Aromatic Compounds
Strategy I: The Order of Events
One-Group C-X Disconnections
Strategy II: Chemoselectivity
Two-Group C-X Disconnections
Strategy III: Reversal of Polarity, Cyclisations, Summary of Strategy
Amine Synthesis
Strategy IV: Protecting Groups
One Group C-C Disconnections I: Alcohols
General Strategy A: Choosing a Disconnection
Strategy V: Stereoselectivity A
One Group C-C Disconnections II: Carbonyl Compounds
Strategy VI: Regioselectivity
Alkene Synthesis
Strategy VII: Use of Acetylenes (Alkynes)
Two-Group C-C Disconnections II: 1,3-Difunctionalised Compounds
Strategy IX: Control in Carbonyl Condensations
Two-Group Disconnections III: 1,5-Difunctionalised Compounds Conjugate (Michael) Addition and Robinson Annelation
Strategy X: Aliphatic Nitro Compounds in Synthesis
Two-Group Disconnections IV: 1,2-Difunctionalised Compounds
Strategy XI: Radical Reactions in Synthesis
Two-Group Disconnections V: 1,4-Difunctionalised Compounds
Strategy XII: Reconnection
Two-Group C-C Disconnections VI: 1,6-diCarbonyl Compounds
General Strategy B: Strategy of Carbonyl Disconnections
Strategy XIII: Introduction to Ring Synthesis: Saturated Heterocycles
Three-Membered Rings
Strategy XIV: Rearrangements in Synthesis
Four-Membered Rings: Photochemistry in Synthesis
Strategy XV: The Use of Ketenes in Synthesis
Five-Membered Rings
Strategy XVI: Pericyclic Reactions in Synthesis: Special Methods for Five-Membered Rings
Six-Membered Rings
General Strategy C: Strategy of Ring Synthesis
Strategy XVII: Stereoselectivity B
Aromatic Heterocycles
General Strategy D: Advanced Strategy

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